T-Cell Non-Hodgkin’s Lymphoma of the Maxillary Sinus: Diagnostic Challenges in the Sinonasal Tract

Abstract

Non-Hodgkin’s lymphoma (NHL) of the sinonasal tract is an exceptionally rare malignancy that poses a significant diagnostic challenge. Differentiating NHL from inflammatory polyps or other non-malignant lesions can be difficult, making accurate diagnosis challenging for ENT surgeons and pathologists. Consequently, it is crucial to perform multiple deep biopsies and ensure adequate sampling in patients with a clinical presentation suggestive of malignancy.
This case report discusses a 55-year-old male who presented with nasal congestion, blood-stained nasal discharge, and facial swelling that had persisted for approximately two months. Initially treated for rhinosinusitis without improvement from local hospitals, a biopsy performed from our centre confirmed the diagnosis of T-cell type of non-Hodgkin’s lymphoma.